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17α estradiol 3 sulphate e0893  (steraloids inc)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
17α Estradiol 3 Sulphate E0893, supplied by steraloids inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ethynylestradiol d4 350820 06 3 steraloids 17  (steraloids inc)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
Ethynylestradiol D4 350820 06 3 Steraloids 17, supplied by steraloids inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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7 57 17α estradiol 57 91 0 natural estrogen steraloids  (steraloids inc)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
7 57 17α Estradiol 57 91 0 Natural Estrogen Steraloids, supplied by steraloids inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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17α estradiol  (Macklin Inc)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
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17α-ethinyl-13c2-estradiol (ee-13c2)  (Cambridge Isotope Laboratories)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
17α Ethinyl 13c2 Estradiol (Ee 13c2), supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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17α-estradiol  (Tokyo Chemical Industry)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
17α Estradiol, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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17α estradiol  (steraloids inc)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
17α Estradiol, supplied by steraloids inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
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17α-estradiol, cayman cat # 20776  (Cayman Chemical)
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DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and <t>E0893</t> and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .
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Image Search Results


DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and E0893 and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .

Journal: Cell Reports Methods

Article Title: Combinatorial responsiveness of chemosensory neurons in mouse explants revealed by DynamicNeuroTracker

doi: 10.1016/j.crmeth.2025.101216

Figure Lengend Snippet: DyNT output displays selective responses of VSNs to bile acids and sulfated steroids (A, C, and E) Representative local MIP images of a neuron that exclusively responded to CA, DCA, and E0893 and P3865, respectively. Yellow masks indicate the target neuron being active. Masks with different colors indicate other neurons throughout (A), (C), and (E). The stimulation information is provided at the lower right. Scale bars, 50 μm. (B, D, and F) Calcium activity response curves of the neurons shown in (A), (C), and (E), respectively, for each stimulus (black). Each trial period is 20 frames (60 s), with each stimulus delivered during the first five frames (15 s). The red curve indicates an averaged response curve over five trials for each stimulus. The black asterisk indicates that the across-trial responses for a stimulus are significantly higher than the ones for Ringer’s ( p < 0.05, one-sided t test). The red asterisk indicates the significance after FDR control (adjusted p < 0.1). (G and H) (G) Local MIP images of a representative neuron that is spontaneously active. (H) Calcium activity response curves of the spontaneously active neuron in (G). Active MIP images are outlined in (G), with corresponding time points indicated by triangles with matching colors in (H). See also , , , and .

Article Snippet: 17α-estradiol-3-sulphate (E0893) , Steraloids Inc. , N/A.

Techniques: Activity Assay, Control